Passion flower leaves were used in Native American medicine to heal bruises and cuts. Its traditional uses by the Cherokees of the southern Allegheny mountains, the Houmas of Louisiana, and the Aztecs of Mexico, are well documented and predate its entry into conventional American and European medicine. It was official in the fourth (1916) and fifth (1926) United States National Formulary and removed in 1936. It was also an approved OTC sedative and sleep aid up until 1978 (Bown, 1995; Leung and Foster, 1996; NF, 1926)1
Passion flower was named such by Spanish explorers because they believed the flowers represented the Crucifixion, or Passion of Christ.